ALERT CONTENT PLACEHOLDER
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About the operation

Transsphenoidal surgery is a procedure that allows the surgeon to remove tumours, cysts or other abnormalities that can affect the pituitary gland and the area around it. Your pituitary gland is a small, bean-shaped structure that lies at the base (bottom) of your brain behind your eyes and produces many different hormones (types of body chemicals) that are critical for survival.

Your surgeon will use an endoscope (a small tube-shaped tool) to see all of the important structures during the procedure. This technique was developed by surgeons at UHN. It is now the preferred way to remove tumours, cysts or other abnormalities from the area around your gland. Doing the surgery in this way can help you have a shorter stay in the hospital and a quicker recovery. Fortunately, most pituitary tumours are not cancerous.

Download a printable version of the full guide:
Transsphenoidal Surgery
Pre-admission Visit
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You must come for your pre-admission appointment before your surgery. If you don't come for your pre-admission visit, your surgery will be cancelled (unless you were given other instructions).

In the weeks before your operation, you will have a pre-admission appointment. This appointment could take 2 to 4 hours, or sometimes longer.

Pre-Admission Clinic
Toronto Western Hospital
Main Pavilion – 1st Floor (Room 406)

What should I bring to my pre-admission appointment?
  • Your health card (OHIP card). If you do not have an OHIP card, please bring another form of government-issued photo ID, such as a driver's license or passport.
  • Any other insurance cards. You will need the policy number of your extended health insurance, if you have any.
  • Your spouse/partner, a trusted friend or family member (to offer you support and be a second set of ears).
  • All the medications you take in their original containers. This includes prescription medications, over-the-counter medicines, vitamins, supplements and herbal or natural products.
  • A list of any questions that you may have about the operation and recovery.
  • The name or phone number of your pharmacy, as well as any medical specialists that you have seen in the past 3 years.
  • If you have had a cardiac stress test, echocardiogram and/or a pulmonary function test in the past 3 years, it would be helpful to bring a copy of the final report with you to this appointment.
What happens during my pre-admission visit?
  • You will have blood tests and routine skin swabs. The swabs are taken from your nose and other areas of your body to check for germs that can cause infections.
  • You may also need an electrocardiogram (ECG) to check your heart and a chest x-ray to check your lungs.
  • You will meet many health care providers during your pre-admission visit. Please feel free to ask them any questions that you may have.
  • A pre-admission nurse will review your health history and give you information to prepare you for your operation, including directions for cleaning your skin, eating before your operation, taking your medications and pain management.
  • A pharmacist will review your medications.
  • At this appointment you may also see an anesthesiologist and an endocrinologist.

Day Before Your Operation
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Don’t eat or drink anything after midnight on the day of your surgery. Your surgery will be cancelled if you do. You may be able to take some medicines the morning of your surgery. The pharmacist or nurse will talk with you about this at your pre-admission appointment.

What should I do the day before my operation?
  • Do not eat or drink after midnight on the night before your operation.
  • If you smoke, do not do so for 24 hours before your operation.
  • Do not drink alcohol for 24 hours before your operation.
  • Remove all nail polish and body piercings.
  • You must have a shower with soap and water to clean your skin the night before and the morning of your operation to reduce the chance of infection after your operation.
Day of Your Operation

Please arrive 2 hours before your scheduled surgery time.

Toronto Western Hospital
Fell Pavilion – 2nd Floor, Room 116
Maps & Directions 

All hospital entrances are open by 6:00 am, however the Leonard entrance (between Nassau and Wales) is easiest to access.

What can I expect during surgery?
  • You will get an Intravenous (IV) that will allow the doctors to give you fluids and medicine through your vein during and after the surgery.
  • A doctor will give you a general anesthesia. This means that you will be asleep during the surgery.
  • You will probably have a catheter (tube) inserted into your bladder. This will allow the doctors to carefully monitor your fluids and urine output.
  • Once you are asleep, your surgeon will insert the small tube (endoscope) into your nose through your sphenoid sinus to your pituitary gland. This will help them see a wider area around your gland.
  • Your surgeon will have to remove a small piece of thin bone at the base of your skull to reach the pituitary gland. They will then make a small incision (cut) to get to the tumour or cyst.
  • Using special instruments, your surgeon will try to remove the tumour or cyst without disturbing the normal pituitary gland.

The surgery usually takes about 2 to 4 hours.

After Your Operation

On this page, you can read all about what to expect during your hospital stay. Or, just click on one of the links below, to get the answer you want right now.

 
What will happen right after my operation?
  • You will wake up in the operating room after the surgery and be taken to the PACU (post anesthetic recovery room). No visitors are allowed at this time.
  • You will usually stay for 1 to 2 hours while the nurses monitor you.
  • When you are stable, you will be taken to the Nursing Unit within the ICU or on 6a. Visitors are allowed to visit you there.
  • Your fluid balance (what you drink and urine output) will be closely monitored through your catheter. This tube will be removed 1 to 2 days after your surgery.
  • Your nurse will continue to check how much you are drinking and urinating. They may ask you to keep a record of this.

 
How will I feel after my operation?
  • Your nose may feel congested (stuffy) after surgery and you may find it difficult to breathe through your nose at first. You may find it easier to breathe through your mouth.
  • You may have gauze covering your nose for any drainage (fluid leaking) that can happen immediately after surgery

 
How can I take care of myself after my operation?

Try to avoid blowing your nose, sneezing, or coughing a lot or hard for 1 to 2 weeks. This will help the inside of your nose heal. It may also reduce your risk of nose bleeds.


 
How long will I stay in the hospital?

Usually, you will be ready to go home about 2 to 3 days after your surgery. The hospital discharge time is before 11:00 am. You need to have a family member or friend take you home.

Before you leave:

  • You will get a discharge package that includes an information sheet, follow-up appointments, and a prescription for medicine, if needed.
  • If you had nasal splints put in (ask about this before you leave), you will have an appointment to have them removed. You should have an appointment time scheduled before you leave the hospital.
  • If your discharge is on the weekend, we will contact you with an appointment in a few days. If you do not receive an appointment, please contact you doctor’s office.
Back at home
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Go to nearest Emergency Department if:

  • Your temperature rises above 38.5 °C or 101 °F and you feel chills.
  • You have a severe headache that does not go away.
  • Daylight causes intolerable pain in your eyes.
  • Your neck becomes very stiff and sore, making it painful to bend your head forward.
  • You are less alert.
  • You have a nose bleed that will not stop.
  • The amount of fluid from your nose doesn’t decrease after 1 week. This may be caused by a CSF leak.
  • You are losing too much fluid from your body:
    • You are urinating (peeing) more than usual.
    • You are getting up 3 to 4 times at night to urinate (pee).
    • You often feel very thirsty.
  • You feel very tired and have very low energy.

Please call your neurosurgeon or Physician Assistant/Nurse Practitioner to let us know that you have had these symptoms and have gone to the emergency department.

It usually takes about 2 to 6 weeks to recover from the surgery, but it can take up to 3 months for some people to feel like their normal self again. Everyone’s recovery time will be different.

If you use a CPAP machine for sleep apnea, please discuss this with your team. You may be asked to wait 2 weeks after the surgery before re-using your machine. Make sure your machine is clean before you start using it again.

How should I care for my nose?

It is important to keep your nose clean and moist while you heal. Use only a normal saline nasal spray to moisten inside your nostrils. Don’t put any creams, ointments or objects into your nose. You can buy saline nasal spray (like Salinex or Simply Saline) at your local drug store.

To clean your nostrils:

  • Spray each nostril with the saline spray at least 5 times a day or more. Do this for at least 3 to 4 weeks. Using saline spray keeps hard crusts from forming in your nose. These hard crusts can slow your healing and block your breathing. Using saline spray will also reduce bad odours from your nose which sometimes can happen after this type of surgery.
  • If you have on-going bad odours from your nose and a lot of congestion (stuffy nose) one month after surgery, continue to use your nasal spray and talk with your ENT or your neurosurgeon. Your smell may be affected for the first few weeks after surgery. This is normal and will be temporary.
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Eating/eliminating

  • Once you get home, you can eat and drink normally. Avoid alcohol for 2 days after your surgery.
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Lifestyle

  • You should be able to slowly return to your normal activities once you get home. Going for walks and doing light activities around the house is fine.
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Showering

  • You can shower, bathe and wash your hair as usual.

Heavy objects/lifting/exerting

For the first 6 weeks:

  • Try not to lift anything heavier than 10 pounds (5 kilograms).
  • Try not to bend forward or strain yourself.
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Exercise

  • Don’t go to the gym or do your regular exercises.
  • Don’t play contact sports (soccer, football, hockey).
  • Don’t swim or submerge your face in water. Talk to your doctor about when you can go swimming at your follow-up appointment.
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Work

  • Most patients are ready to return to work in 4 to 8 weeks. As you feel better, slowly return to your normal daily activities..

Driving

  • You can travel by car once you feel ready. This may take a couple of days. Having surgery may make you feel more tired than usual, so only drive short distances at first.
  • If you had vision problems before surgery, make sure your vision is checked before you drive. Follow up with your optometrist or ophthalmologist.
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Traveling by plane

  • If you plan to travel by airplane before your first post-operative clinic visit, please discuss this with your neurosurgeon first.
Who do I call if I experience complications?

Go to nearest Emergency Department if:

  • Your temperature rises above 38.5 °C or 101 °F and you feel chills.
  • You have a severe headache that does not go away.
  • Daylight causes intolerable pain in your eyes.
  • Your neck becomes very stiff and sore, making it painful to bend your head forward.
  • You are less alert.
  • You have a nose bleed that will not stop.
  • The amount of fluid from your nose doesn’t decrease after 1 week. This may be caused by a CSF leak.
  • You are losing too much fluid from your body:
    • You are urinating (peeing) more than usual.
    • You are getting up 3 to 4 times at night to urinate (pee).
    • You often feel very thirsty.
  • You feel very tired and have very low energy.

Please call your neurosurgeon or Physician Assistant/Nurse Practitioner to let us know that you have had these symptoms and have gone to the emergency department.

Who do I call with general post-operative questions?

If you have any questions, please call the Pituitary Clinic at 416 603 5463.


Follow-up appointments

You will have a follow-up appointment scheduled in the Pituitary Clinic. At this appointment, you will see either Dr. Zadeh or Dr. Gentili, and Dr. Ridout, our endocrinologist.

Your first appointment

When
Approximately 6 to 8 weeks after surgery.

Where
Pituitary Clinic
Toronto Western Hospital
West Wing 7– 4th Floor

What to Expect

  • Your doctor will examine you and check your progress.
  • You may have blood tests done to check how well your pituitary gland is working after surgery.
  • You will get an appointment for an MRI. It may be before or after your first post-operative visit. This test will let your doctor see pictures of the area around the pituitary gland after surgery.
  • You may get an appointment to see an ear, nose and throat (ENT) specialist, if needed.
  • You may also get an appointment for an eye test. Your pituitary gland is close to your eye nerve. This test will check if your vision was affected by the surgery.
  • You can talk to your doctor about any concerns or ask any questions you may have.

What to Bring

  • Health card.
  • If you had a CT or MRI outside UHN after your surgery, please bring the images with you on a disk.

Do you live outside the GTA?
If you live at a distance from Toronto, a telehealth appointment may be possible. Please discuss this with our staff.

Your second appointment

When
3 months after surgery

Where
Pituitary Clinic

What to Expect

  • Our team will check how you are recovering and review your recent imaging and labs with you.
  • We will also schedule your yearly appointment during this time.

What to Bring

  • Health card.
  • If you had a CT or MRI outside UHN since your last appointment, please bring the images and report with you on a disk.
  • Print outs of any visual fields done outside the UHN since we saw you last.

Do you live outside the GTA?
Some follow-up appointments may be possible via telehealth for people who live at a distance. Please discuss this with our staff.

Directory

To make or change appointments, call Pituitary Clinic 416 603 5463.

To Contact Your Neurosurgeon’s office:

Dr. Gelareh Zadeh
Phone: 416 603 5679

If you have questions about your post-operative care, you may contact:
Leslie St. Jacques, Physician Assistant: 416 603 5800, ext. 3613

Please note that messages left at this voicemail may not be received until the next business day. If you have a medically urgent concern, please go directly to the Emergency Department.


My contacts
Who do I call if I experience complications?

Go to the nearest emergency department if you have any of the following:

  • Your temperature rises above 38.5 °C or 101 °F and you feel chills.
  • You have a severe headache that does not go away.
  • Daylight causes intolerable pain in your eyes.
  • Your neck becomes very stiff and sore, making it painful to bend your head forward.
  • You are less alert.
  • You have a nose bleed that will not stop.
  • The amount of fluid from your nose doesn’t decrease after 1 week. This may be caused by a CSF leak.
  • You are losing too much fluid from your body:
    • You are urinating (peeing) more than usual.
    • You are getting up 3 to 4 times at night to urinate (pee).
    • You often feel very thirsty.
  • You feel very tired and have very low energy.

Please call your neurosurgeon or Physician Assistant/Nurse Practitioner to let us know that you have had these symptoms and have gone to the emergency department.

Who do I call with general post-operative questions?

If you have any questions, please call the Pituitary Clinic at 416 603 5463.

Directory

To make or change appointments, call Pituitary Clinic 416 603 5463.

To Contact Your Neurosurgeon's office:

Dr. Gelareh Zadeh
Phone: 416 603 5679

If you have questions about your post-operative care, you may contact:
Leslie St. Jacques, Physician Assistant: 416 603 5800, ext. 3613

Please note that messages left at this voicemail may not be received until the next business day. If you have a medically urgent concern, please go directly to the Emergency Department.


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