Cancer Clinical Research Unit

Inclusion Criteria: - BMI ≥ 35 - Diagnosis of grade 1 endometrioid endometrial cancer or complex atypical hyperplasia - Clinical stage 1 disease - no evidence of metastatic disease beyond the uterus by physical exam or imaging performed (MRI, CT) - ECOG status 5 years - Evidence of adenomyosis seen on MRI - Previous major upper abdominal surgery (ex. splenectomy, partial gastrectomy, liver resection, bowel resection). *Appendectomy, cholecystectomy, hernia repair, and caesarean section are acceptable procedures for inclusion - Current use of weight loss medication - Contraindications to sleeve gastrectomy - Medical co-morbidity with end-organ dysfunction - Unable to understand and participate in the informed consent process - Currently pregnant