Summary
Our research program focuses on resolving the pathogenesis and defining the optimal management of ankylosing spondylitis (AS).
The basic science approaches include molecular biology, genomics and proteomics as applied to animal models of AS and to immunophenotyping of cells from AS patients.
The clinical studies include defining prognostic factors in AS, response profiles to biologic agents, and decision analysis in diagnostic algorithms.
Team Members
- Ali Akram, Postdoctoral Fellow
- Gillian Fitzgerald, Clinical Research Fellow
- Daeria Lawson, Graduate Student
- Melissa Lim, Lab Technician
- Aki Nakamura, Clinical Research Fellow
- Ejaz Pathan, Clinical Research Fellow
- Zoya Qaiyum, Graduate Student
- Anthony So, Graduate Student
- Michael Tang, Postdoctoral Fellow
- Sophie Wojcik, Clinical Research Fellow
Keywords
Immunology; genetics; spondylitis; inflammation; cytokines
Profiles
Summary
Dr. Kapoor is the Co-Director of the Schroeder Arthritis Institute. He is the Tony and Shari Fell Platinum Chair in Arthritis Research - Canada Research Chair (Tier 1), a Professor at the University of Toronto and a Senior Scientist at the Krembil Research Institute.
Dr. Kapoor's translational research program is directed towards:
- Understanding the complex cellular and molecular mechanisms associated with joint destruction during osteoarthritis.
- Identifying reliable biomarkers for early identification of patients with osteoarthritis to enable early intervention.
- Identifying novel therapeutic targets to stop/delay osteoarthritis and restore joint function.
- Understanding key endogenous mechanisms associated with fibrosis during osteoarthritis and connective tissue diseases.
Team Members
- Keemo Delos Santos, Sequencing Technician
- Dr. Osvaldo Espin-Garcia, Biostatistician
- Dr. Noah Fine, Scientific Associate
- Maryam Gabrial, Administrative Assistant
- Himanshi Gupta, Histology Technician
- Katrina Hueniken, Biostatistician
- Dr. Paramvir Kaur, Postdoctoral Fellow
- Dr. Nikita Looby, Metabolomics Specialist
- Anca Maglaviceanu, PhD Student
- Hayley Peters, Master's Student
- Evan Pollock Tahiri, Animal Technician
- Pratibha Potla, Senior Bioinformatician
- Behdad Ravarian, Animal Technician
- Dr. Jason Rockel, Scientific Associate
- Lynn Saber, Digital Content & Communications Specialist
- Dr. Amit Sandhu, Postdoctoral Fellow
- Kabriya Thavaratnam, PhD Student
- Dr. Shaba Vohra, Senior Bioinformatician
- Christina Ward, Research Manager
Keywords
Cartilage degeneration; fibrosis; biomarkers; genetically modified mice; OA tissue biobanking
Research Lab
Kapoor Lab
Profiles
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